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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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規(guī)格

庫存

目錄價

會員專享價

數(shù)量

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基本信息

英文名稱	Secalciferol (Synonyms: (24R)-24,25-Dihydroxyvitamin D3)
中文名稱	(3R,6R)-6-((1R,3aS,7aR,E)-4-((Z)-2-((S)-5-羥基-2-亞甲基亞環(huán)己基)亞乙基)-7a-甲基八氫-1H-茚-1-基)-2-甲基庚烷-2,3-二醇; 司骨化醇
CAS號	55721-11-4
分子式	C??H??O?
分子量	416.64
MDL	MFCD00941417
外觀	White to off-white powder
儲存條件	-20°C, protect from light, stored under nitrogen

產(chǎn)品詳情

Secalciferol, also known as (24R)-24,25-Dihydroxyvitamin D3, is the primary active form of Vitamin D. This compound potently activates the vitamin D receptor (VDR) with an EC50 value of 150 nM. It plays a crucial role in various biological processes, including the regulation of calcium homeostasis, cellular differentiation, and proliferation. Additionally, Secalciferol has significant implications for the immune system, making it a promising area of research for conditions such as rickets, osteomalacia, hypercalcemia, and autoimmune disorders.

相關(guān)文獻(xiàn)

Profiling of Vitamin D Metabolic Intermediates toward VDR Using Novel Stable Gene Reporter Cell Lines IZ-VDRE and IZ-CYP24[J].

PMID: 27327272 DOI: 10.1021/acs.chemrestox.6b00170

PMID: 10498030 DOI: 10.1016/s0039-128x(99)00057-4

J Toxicol Sci. 1999 May;24(2):133-9.

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