| 英文名稱 | PHA-543613 | 
|---|---|
| 中文名稱 | PHA-543613 | 
| CAS號 | 478149-53-0 | 
| 分子式 | C15H17N3O2 | 
| 分子量 | 271.31 | 
| 外觀 | White to off-white powder | 
| 英文名稱 | PHA-543613 | 
|---|---|
| 中文名稱 | PHA-543613 | 
| CAS號 | 478149-53-0 | 
| 分子式 | C15H17N3O2 | 
| 分子量 | 271.31 | 
| 外觀 | White to off-white powder | 
PHA-543613 is a potent, orally bioactive, BBB (blood-brain barrier)-crossing, and selective α7 nAChR agonist with Ki of 8.8 nM. PHA-543613 is more selective for α7-nAChR than α3β4, α1β1γδ, α4β2 and 5-HT3 receptors. PHA-543613 may be used to study cognitive deficits in Alzheimer's disease (AD) and schizophrenia.