RMC-6236 | RAS-IN-2 | 2765081-21-6

規(guī)格	庫存	目錄價	會員專享價	數量
1 mg	3-5 days	￥2366.00	登錄后可見	- +
5 mg	3-5 days	￥5788.00	登錄后可見	- +
10 mg	3-5 days	￥9388.00	登錄后可見	- +

規(guī)格

庫存

目錄價

會員專享價

數量

1 mg

3-5 days

￥2366.00

登錄后可見

- +

5 mg

3-5 days

￥5788.00

登錄后可見

- +

10 mg

3-5 days

￥9388.00

登錄后可見

- +

基本信息

英文名稱	RMC-6236 (Synonyms: RAS-IN-2)
中文名稱	RMC-6236 \| RAS-IN-2
CAS號	2765081-21-6
分子式	C43H56N8O5S
分子量	797.02
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

RMC-6236 is a RAS(ON)MULTI inhibitor with anticancer activity and is used in the study of advanced malignant solid tumors and colorectal cancer.
RMC-6236 is an orally active, non-covalent RAS (ON) inhibitor. RMC-6236 disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, with EC50 values ranging from 28-220 nM for wild-type KRAS, NRAS, HRAS, and multiple oncogenic RAS variants. RMC-6236 inhibits pERK. RMC-6236 has anti-tumor activity against KRAS mutant tumors.
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PMID: 38593348 PMCID: PMC11149917 DOI: 10.1158/2159-8290.CD-24-0027

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CL2789

RMC-6236 | RAS-IN-2

2765081-21-6 98+% 3-5 days

￥2366.00 1 mg

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RMC-6236 | RAS-IN-2

RMC-6236 (Synonyms: RAS-IN-2)

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