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達羅托組單抗

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Dalotuzumab (Anti-IGF1R / CD221)

產(chǎn)品編號:CLA1248 CAS No.:1005389-60-5 MDLNo: 分子式: 分子量:
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
1 mg 3-5days ¥3000.00 登錄后可見
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5 mg 3-5days ¥12500.00 登錄后可見
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10 mg 3-5days ¥20000.00 登錄后可見
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50 mg 3-5days ¥80000.00 登錄后可見
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100 mg 3-5days ¥125000.00 登錄后可見
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基本信息
英文名稱 Dalotuzumab (Anti-IGF1R / CD221)
中文名稱達羅托組單抗
CAS號1005389-60-5
儲存條件Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.
產(chǎn)品詳情

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R . Dalotuzumab acts by inhibiting IGF-1 - and IGF-2 -mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.

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